Anti-Therapeutic Action: inflammation

Patulin Biodegradation by Rhodosporidiobolus ruineniae and Meyerozyma guilliermondii Isolated From Fruits

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Patulin is a dangerous toxin produced by molds that grow on apples and peaches, posing serious health risks to consumers. Researchers isolated two yeast species from fruits that can effectively break down patulin into a less toxic compound called (E)-ascladiol. The yeasts work by using enzymes inside their cells to degrade the toxin, and this biological approach could be used to safely remove patulin from contaminated fruits and fruit products.

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Kidney Injury Induced by High-Dose Chaga Mushroom Consumption: Experimental Evidence in a Rat Model

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This study examined whether consuming large amounts of Chaga mushroom can damage the kidneys in rats. The researchers found that high-dose Chaga consumption led to kidney injury through accumulation of oxalate (a naturally occurring compound in the mushroom), causing oxidative damage and cell death in kidney tissue. The findings suggest that while Chaga mushroom is promoted as a health supplement, excessive long-term consumption may harm kidney function, particularly in susceptible individuals.

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Yamabushitake Mushroom (Hericium erinaceus (Bull.) Pers. 1797) Mycelium Improves Reproductive System Dysfunction in Male Rats Induced by Polystyrene Microplastics

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A study found that Yamabushitake mushroom extract can help protect male reproductive health from damage caused by polystyrene microplastics found in everyday plastic products. The mushroom’s active compound, erinacine A, reduced inflammation and oxidative stress in rats, improved hormone levels, and enhanced sperm quality. This research suggests the mushroom could be developed into a supplement for men concerned about their fertility and reproductive health in our plastic-filled environment.

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Flagellate Dermatitis by Shiitake Mushroom

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This case study describes a young man who developed whip-like linear rashes on his skin a few days after eating shiitake mushrooms. The rash, called flagellate dermatitis, is caused by a heat-sensitive substance in undercooked shiitake called lentinan. The condition is harmless and disappeared completely within a week after applying a steroid cream, highlighting the importance of cooking shiitake thoroughly to prevent this reaction.

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