Anti-Therapeutic Action: immunosuppression

Enhancing Environmental and Human Health Management Through the Integration of Advanced Revitalization Technologies Utilizing Artificial Intelligence

This paper describes how combining artificial intelligence with environmental monitoring can help us better understand how pollution harms our health. The authors propose a seven-step system that collects data on pollution levels in air, water, and soil alongside health information from communities. By using AI to analyze these massive datasets together, scientists and doctors can more quickly identify which pollutants are causing specific health problems and design better treatments for affected people and environments.

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A comprehensive review of mycotoxins, their toxicity, and innovative detoxification methods

Mycotoxins are poisons produced by molds that commonly contaminate foods like grains, nuts, and spices, causing serious health problems in people and animals. This comprehensive review examines how these toxins affect our health, how to detect them in food, and various methods to remove or destroy them. Traditional approaches using biological agents and chemicals work well but are only partially effective, while newer innovative methods using nanoparticles and plant extracts show greater promise for more complete protection of our food supply.

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Tumor-associated macrophages in tumor progression and the role of traditional Chinese medicine in regulating TAMs to enhance antitumor effects

This review explains how tumor-associated macrophages (immune cells) can either fight or help cancer depending on their type. Traditional Chinese Medicine contains compounds that can reprogram these macrophages to fight cancer more effectively. By shifting macrophages from a cancer-supporting state to a cancer-fighting state, TCM treatments could enhance the body’s natural ability to combat tumors and reduce side effects of conventional cancer therapies.

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Heavy Metal Poisoning and Its Impacts on the Conservation of Amazonian Parrots: An Interdisciplinary Review

Amazonian parrots face a serious but often invisible threat from heavy metal poisoning caused by illegal mining, agriculture, and urban waste. These toxic metals accumulate in the birds’ bodies over their long lifespans, causing brain damage, kidney failure, and reproductive problems that threaten entire parrot populations. The review calls for urgent action including stopping illegal mining, cleaning contaminated areas, and protecting forests to ensure these important seed-dispersing birds survive.

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Increased Dissemination of Aflatoxin- and Zearalenone-Producing Aspergillus spp. and Fusarium spp. during Wet Season via Houseflies on Dairy Farms in Aguascalientes, Mexico

This study found that during rainy seasons on Mexican dairy farms, houseflies carry more mold spores that produce harmful toxins called aflatoxins and zearalenone. These toxins contaminate cattle feed and milk, posing health risks to both animals and humans. The research shows that controlling houseflies during wet seasons is crucial to reduce toxic mold contamination of dairy products and animal feed.

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Comparative genome analysis of patulin-producing Penicillium paneum OM1 isolated from pears

Researchers sequenced the complete genome of a mold called Penicillium paneum that produces a toxic substance called patulin, which contaminates apples and pears. They found all 15 genes responsible for making patulin and discovered the mold has similar genetic patterns to other patulin-producing fungi. This information could help scientists develop better ways to prevent patulin contamination on fruit crops and improve food safety.

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Negative Effects of Occurrence of Mycotoxins in Animal Feed and Biological Methods of Their Detoxification: A Review

Molds that grow on grains and feed produce toxic substances called mycotoxins that can seriously harm farm animals, causing liver and kidney damage, reproductive problems, and reduced productivity. While proper storage and farming practices help prevent contamination, some mycotoxins still get through. Recent research shows that beneficial bacteria like those in yogurt and certain yeasts can effectively remove these toxins from animal feed, making it safer for livestock while protecting the environment from harmful chemicals.

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Recent innovations and challenges in the treatment of fungal infections

Fungal infections are becoming more common and dangerous, especially for people with weakened immune systems, and many fungi are developing resistance to current medications. Doctors and researchers are developing new treatment strategies, including combining multiple drugs together and using advanced technologies to deliver medicines more effectively to infected areas. Natural compounds from plants and new biotechnology tools like genetic engineering and nanoparticles show promising results for fighting drug-resistant fungal infections.

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Incidence And Risk Factors for Invasive Fungal Infections in Pre-Transplant and Transplant-Ineligible Multiple Myeloma in the U.S.: A Claims Analysis (2017-2021)

This study examined fungal infections in patients with multiple myeloma who were not eligible for or preparing for stem cell transplants. Researchers found that 6% of these patients developed invasive fungal infections, with yeast infections being the most common type. The risk of these infections was significantly higher in patients taking dexamethasone (a steroid) or those with low white blood cell counts and those receiving multiple cancer therapies.

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Newly Discovered Fungal Species from Black Pepper Marketed in Brazil: Penicillium pipericola sp. nov. and Syncephalastrum brasiliense sp. nov.

Researchers in Brazil discovered two new fungal species found on commercially sold black pepper. While one species can produce a toxic compound that concerns food safety experts, both species also produce molecules with potential medical benefits, including compounds that may help fight cancer and neurological diseases. This discovery highlights the importance of monitoring fungi in food products while also revealing unexpected pharmaceutical potential hidden in everyday spices.

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