Anti-Therapeutic Action: hypertension

Lysergic Acid Diethylamide (LSD) and the Heart: Exploring the Potential Impacts of LSD on Cardiovascular Function

This review examines how LSD affects the heart and blood vessels. While some evidence suggests LSD might protect against heart disease by reducing inflammation and blood clots, acute use can dangerously raise heart rate and blood pressure, and cause blood vessel constriction. Regular low-dose use raises concerns about potential valve damage. More research is needed to understand the full cardiovascular safety of LSD before it can be considered for medical use.

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Assessment of Heavy Metals in Mexican Dietary Supplements Using Total X-Ray Fluorescence Spectrometry and Health Risk Evaluation

Mexican dietary supplements commonly contain toxic heavy metals like lead, arsenic, and chromium. While individual metal levels in most supplements appeared safe when consumed alone, the cumulative exposure from multiple metals could increase cancer risk over a lifetime. The study found that some popular supplements, particularly those marketed for weight loss and blood detoxification, contained concerning metal levels, especially seaweed-based products and animal-origin supplements. Better regulation and labeling of dietary supplements in Mexico is urgently needed to protect consumers from long-term health risks.

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Psilocybin therapy and anorexia nervosa: a narrative review of safety considerations for researchers and clinicians

This review examines the safety of psilocybin therapy for treating anorexia nervosa, a serious eating disorder with limited treatment options. The authors analyze how psilocybin’s common side effects (like increased heart rate, nausea, and dizziness) interact with medical complications already present in people with anorexia. Based on early clinical trials, they conclude that psilocybin can be safely used in this population with proper medical screening and monitoring protocols tailored to their specific vulnerabilities.

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Current situation regarding psychedelics and magic mushroom in Korea

This article reviews the current status of psychedelic mushrooms and their potential medical uses in Korea. Several wild mushroom species containing psilocybin have been identified in Korea and can cause hallucinations and other nervous system effects lasting a few hours. While psychedelics show promise for treating depression and anxiety, Korea currently classifies them as controlled substances, and only approved clinical trials can be conducted with government permission.

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Toxicology and Analysis of Psychoactive Tryptamines

Tryptamines are a growing class of psychoactive drugs that can cause hallucinations and other dramatic changes in perception. These substances, including compounds like DMT and psilocybin from magic mushrooms, work by affecting serotonin receptors in the brain. While some research explores their potential medical use for treating depression and anxiety, they also carry serious risks including dangerous changes in heart rate, body temperature, and mental state. Scientists have developed new laboratory methods to detect these drugs in blood and urine samples to help doctors diagnose and treat overdoses.

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Effects of hallucinogenic drugs on the human heart

Hallucinogenic drugs like LSD and psilocybin affect not only the brain but also the heart. These drugs increase heart rate and contractility mainly through specific serotonin and histamine receptors. While these effects might have therapeutic potential for psychiatric conditions, prolonged use can damage heart valves and cause dangerous arrhythmias. Understanding these cardiac effects is crucial for safe medical use and treatment of overdoses.

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Scoping Review: The Role of Psychedelics in the Management of Chronic Pain

This review examines how psychedelic drugs like LSD and psilocybin might help treat chronic pain conditions such as cluster headaches and phantom limb pain. The researchers found nine studies suggesting these substances could reduce pain by affecting serotonin receptors in the brain. While early results are promising, more rigorous clinical trials are needed before these drugs can become standard pain treatments. The authors note that strict legal restrictions on psychedelics currently limit research opportunities.

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