Anti-Therapeutic Action: Fg12 suppresses beneficial bacteria Bacillus and Pseudomonas

Inhibition of RNase to Attenuate Fungal-Manipulated Rhizosphere Microbiome and Diseases

Fusarium fungi cause devastating crop diseases by producing a protein called Fg12 that acts like a molecular weapon to kill beneficial bacteria in the soil around plant roots. Scientists discovered that a simple compound called GMP can block this fungal weapon, preventing the pathogen from suppressing protective bacteria. By treating seeds or soil with GMP, farmers can significantly reduce root rot in soybeans and alfalfa while promoting plant growth.

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