Anti-Therapeutic Action: Elevated minimum inhibitory concentrations to itraconazole and fluconazole indicating reduced antifungal susceptibility

Targeted long-read sequencing analysis and antifungal susceptibility profiles of Sporothrix schenckii isolates from Thailand

This research examined a fungal infection called sporotrichosis found in Thailand, particularly in cats and humans. Scientists used advanced DNA sequencing technology to accurately identify which species of the fungus caused the infections and understand how they are related to each other. They also tested how well common antifungal medications work against these fungi, finding that some strains have become resistant to itraconazole, the main drug used to treat sporotrichosis.

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