Anti-Therapeutic Action: DNA damage

Role of Genetically Modified Microorganisms for Effective Elimination of Heavy Metals

Heavy metals like lead, mercury, and arsenic are dangerous pollutants that accumulate in our environment and food chain, causing serious health problems. Traditional methods to remove these metals are expensive and inefficient. Scientists have created genetically modified bacteria and fungi that are much better at absorbing and breaking down heavy metals from contaminated water and soil, offering a cheaper and more environmentally friendly solution to clean up pollution.

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Green Synthesis of Copper Nanoparticles from the Aqueous Extract of Lonicera japonica Thunb and Evaluation of Its Catalytic Property and Cytotoxicity and Antimicrobial Activity

Scientists created tiny copper particles using honeysuckle plant extract in an environmentally friendly way. These particles work well for cleaning dyes from water and killing harmful bacteria and fungi. However, they can be toxic to human cells at high concentrations, so careful dosing is important for medical applications.

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Integration of Physiological, Transcriptomic and Metabolomic Reveals Molecular Mechanism of Paraisaria dubia Response to Zn2+ Stress

This research shows that a fungus called Paraisaria dubia can effectively clean up zinc pollution by removing 60% of zinc from contaminated environments. The fungus uses multiple survival strategies when exposed to zinc stress, including producing more protective slime-like substances on its surface and generating spores that are more resistant to harmful conditions. By studying the fungus at the molecular level, scientists discovered which genes and chemical compounds activate these protective responses, paving the way for using fungi as natural cleaners for heavy metal-contaminated soil and water.

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Biological approaches to mitigate heavy metal pollution from battery production effluents: advances, challenges, and perspectives

Battery factories produce dirty water containing harmful heavy metals like lead and cadmium. Instead of using expensive chemical treatments, scientists are finding natural ways to clean this water using plants, bacteria, and other living organisms. These biological methods can remove up to 99% of the metals and are better for the environment. This review examines all these natural cleaning methods and suggests ways to make battery production cleaner and safer.

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Aflatoxin B1 (AFB1) biodegradation by a lignolytic phenoloxidase of Trametes hirsuta

Scientists discovered that a mushroom called Trametes hirsuta produces a special enzyme that can break down aflatoxin B1, a dangerous toxin that contaminates foods like peanuts, corn, and nuts. This enzyme is unique because it works without needing additional chemicals as helpers, making it practical for real-world use. The enzyme successfully degraded 77.9% of the toxin under simple conditions, and researchers suggest it could be applied directly to contaminated food surfaces as a safe, natural way to reduce food poisoning risks.

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Environmental Impact of Xenobiotic Aromatic Compounds and Their Biodegradation Potential in Comamonas testosteroni

This review examines how aromatic compounds found in plastics, pesticides, and antibiotics pollute our environment and how bacteria like Comamonas testosteroni can break them down naturally. The research shows that microplastics are accumulating in oceans and wildlife, causing health problems ranging from physical damage to disruption of metabolism and development. Scientists are exploring ways to use these bacteria and microbiome engineering to create biological cleaning systems that could sustainably treat pollution without adding more chemicals to the environment.

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Heavy Metal-Contaminated Soils and Gastric Cancer Risk: Molecular Insights and the Relevance of a One Health Perspective

Heavy metals like cadmium, arsenic, and lead contaminate agricultural soils and accumulate in crops such as rice and vegetables, which people consume as part of their daily diet. These metals damage stomach cell DNA and trigger inflammation, increasing cancer risk, especially when combined with bacterial infections like H. pylori. A comprehensive approach monitoring soil quality, crop safety, and human health together can help prevent this disease and protect communities from contamination.

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Fungal Metabolomics: A Comprehensive Approach to Understanding Pathogenesis in Humans and Identifying Potential Therapeutics

This review explains how scientists use metabolomics—a technique that identifies all chemical compounds in organisms—to understand how fungi cause disease and resist medicines. Fungi produce many different chemicals that help them attack our bodies and survive treatments, but these same chemicals could also be used to create new medicines. By studying these fungal chemicals, researchers can develop better antifungal drugs and understand how fungi manage to evade our immune system.

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Molecular mechanisms of metal toxicity and transcriptional/post-transcriptional regulation in plant model systems

Plants face serious damage from heavy metals like cadmium, arsenic, and chromium in contaminated soils and water. Scientists are discovering how plants defend themselves through changes in gene expression, special proteins that trap metals, and modifications to their DNA that control stress response genes. Understanding these natural defense mechanisms could help us develop crops that survive in polluted environments and remove heavy metals from contaminated areas, making food safer and protecting human health.

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Innovative Approaches and Evolving Strategies in Heavy Metal Bioremediation: Current Limitations and Future Opportunities

Heavy metals like lead, mercury, and arsenic accumulate in soil and water, harming both ecosystems and human health. Traditional cleanup methods are expensive and harmful to the environment. Scientists are developing biological solutions using microorganisms and special plants that can absorb or break down these toxic metals, combined with genetic engineering and nanotechnology to make the process faster and more effective.

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