Anti-Therapeutic Action: disease progression

Optimization of cultural conditions for pectinase production by Diaporthe isolate Z1-1N and its pathogenicity on kiwifruit

Researchers studied how a fungus called Diaporthe causes soft rot in kiwifruit by producing special enzymes called pectinases that break down the fruit’s cell walls. They found the best conditions for growing these enzymes in the lab: a temperature of 28°C, neutral pH around 7.5, and 2-3 days of growth. When they extracted these pure enzymes and put them on fresh kiwifruit, the enzymes caused damage equivalent to about half the damage caused by the living fungus itself, proving these enzymes are important for disease development.

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Rhinocerebral Mucormycosis in a Patient With Diabetes: A Rare but Critical Infection in the United Arab Emirates

A middle-aged man with undiagnosed diabetes developed a serious fungal infection called mucormycosis that affected his sinuses, eyes, and brain. He presented with flu-like symptoms and facial weakness, and blood tests showed dangerously high blood sugar and acid levels (diabetic ketoacidosis). Doctors treated him with multiple rounds of antifungal medications, several surgeries, and innovative injections directly into and around his eyes and spinal cord, resulting in his successful recovery and discharge.

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