Anti-Therapeutic Action: cytotoxicity to fibroblast cells at high concentrations (above 50 μg/mL)

Comparative Study and Transcriptomic Analysis on the Antifungal Mechanism of Ag Nanoparticles and Nanowires Against Trichosporon asahii

Researchers compared two types of tiny silver particles (nanoparticles and nanowires) as potential treatments for a dangerous fungal infection caused by Trichosporon asahii. Silver nanowires were found to be more effective than nanoparticles at killing the fungus by damaging its cell membranes and disrupting its energy production. The study identified 15 key genes involved in how silver nanowires attack the fungus, suggesting these nanomaterials could become useful alternatives to traditional antifungal drugs.

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