Sandalwood Sesquiterpene (Z)-α-Santalol Exhibits In Vivo Efficacy Against Madurella mycetomatis in Galleria mellonella Larvae
Researchers tested sandalwood oil components against a fungal disease called eumycetoma that causes serious skin infections, especially in tropical regions. They found that one component called (Z)-α-santalol was highly effective at killing the fungus and extending survival in laboratory-infected moth larvae, while actually being relatively safe. This natural compound shows promise as a potential new treatment for this neglected disease that currently relies on expensive drugs that are only 40% effective.