Anti-Therapeutic Action: corneocyte detachment

Aspartyl protease MfSAP2 is a key virulence factor in mycelial form of skin fungi Malassezia furfur

Malassezia furfur is a common skin fungus that can change from round yeast cells to thread-like filaments. When it becomes thread-like, it produces a special enzyme called MfSAP2 that damages the proteins holding together the dead skin cells that form our skin’s protective barrier. This damage may be responsible for the patches and discoloration seen in pityriasis versicolor, a common skin condition.

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