Researchers tested whether artificial intelligence chatbots like ChatGPT and Microsoft Copilot could help doctors diagnose histoplasmosis, a serious fungal infection affecting people with HIV/AIDS that is often missed. They presented 20 real patient case descriptions to different AI systems and found that Microsoft Copilot performed best, correctly identifying histoplasmosis in 90% of cases—about as good as laboratory tests. While the AI showed promise as a helpful tool to suggest this neglected disease during diagnosis, doctors would still need to verify findings with actual tests.