Anti-Therapeutic Action: biofilm formation

mGem: Submarine mycology—an analog to astromycology

Scientists are studying fungi in submarines to better understand fungal health risks for astronauts in space. Both submarines and spacecraft are enclosed environments where fungi can grow, causing infections and other health problems. The same types of fungi found growing in submarines have been detected on the International Space Station. By learning from decades of submarine research, space agencies can better prepare for and prevent fungal-related health issues during long space missions.

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Candida albicans Goliath cells pioneer biofilm formation

When Candida albicans fungi run out of zinc, they transform into larger cells called ‘Goliath cells’ that are exceptionally sticky to plastic surfaces. Scientists found that these Goliath cells are much better at sticking to catheters and other medical devices than regular yeast cells, even when blood is flowing past them. This discovery helps explain why fungal infections on catheters are so common and could lead to better ways to prevent these dangerous infections that affect hospitalized patients.

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