Anti-Therapeutic Action: acute kidney injury

Vaping danger: A hidden threat among Malaysia’s youth

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A 15-year-old student in Malaysia was hospitalized after vaping a product labeled as having a magic mushroom flavor. Testing revealed the vape actually contained MDMB-4en-PINACA, a highly potent synthetic cannabinoid that is 100-200 times stronger than natural cannabis. This case highlights the danger of unregulated vaping products being mixed with illegal substances that can cause serious health effects including seizures, heart problems, and organ damage. Doctors and the public need to be aware of these hidden threats in vaping products.

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Candida glabrata meningitis in a patient with newly diagnosed acquired immunodeficiency syndrome from Sikkim, India

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A middle-aged woman in India was admitted with severe headaches and was found to have a rare fungal infection of the brain (meningitis) caused by Candida glabrata, a type of yeast. She had recently been diagnosed with AIDS and had very low immune cell counts. Although doctors tried multiple antifungal medications, the yeast showed resistance to these drugs and the patient’s condition worsened, ultimately leading to her death. This case highlights how dangerous fungal infections can be in people with severely weakened immune systems.

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Educational Case: Acetaminophen hepatotoxicity: Pathophysiology and evaluation of acute liver failure

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This educational case describes how acetaminophen overdose causes severe liver damage leading to acute liver failure. The toxic form of acetaminophen damages liver cell mitochondria and causes widespread cell death, particularly in the center of liver lobules. Treatment with N-acetylcysteine within 24 hours of overdose significantly improves outcomes, though severe cases require liver transplantation.

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Pulmonary Mucormycosis in Diabetic Patients: A Case Series From a Tertiary Respiratory Center in Sri Lanka

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This case study describes three patients with diabetes who developed a serious lung infection caused by a rare fungus called mucormycosis. The infection presented with various symptoms like cough, fever, and weight loss, and was diagnosed using lung tissue samples that showed the characteristic fungal structures. Two patients recovered with prolonged antifungal medication treatment, while one patient unfortunately died despite receiving prompt treatment, highlighting how serious this infection can be.

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