The Medicinal Values of Culinary-Medicinal Royal Sun Mushroom (Agaricus Blazei Murrill)

Summary

This research examines the health benefits of Agaricus blazei Murrill (ABM), a medicinal mushroom from Brazil that has shown promising therapeutic potential for various diseases. The mushroom contains natural compounds that can boost immune function and help fight multiple health conditions. Impacts on everyday life: • Could provide a natural supplement option for supporting immune system health • May offer complementary treatment options for cancer patients • Shows potential as a natural approach to managing diabetes and cholesterol • Provides a safe dietary supplement for general health maintenance • Represents a sustainable and natural source of medicinal compounds

Background

Agaricus blazei Murrill (ABM) is a basidiomycete brown fungus native to Brazil, known as ‘Cogumelo do Sol’ in Brazil or ‘Himematsutake’ in Japan. Mushrooms have historically been used as food sources due to their low caloric content and high nutritional value in minerals, vitamins, fibers, and essential amino acids. In recent years, there has been increased interest in ABM for therapeutic and medicinal purposes.

Objective

This review aims to demonstrate and summarize the various pharmacological effects of Agaricus blazei Murrill (ABM) to provide reference for future studies and applications against different diseases.

Results

The review found that ABM contains multiple bioactive compounds, particularly polysaccharides and β-glucans, which demonstrate significant therapeutic potential. Key findings include anticancer activity against various tumor cells, antiviral effects against poliovirus and HSV, liver protective properties, immunomodulating effects, antidiabetic activity, and effectiveness against leishmaniasis. The mushroom also showed anti-inflammatory, antiallergic, and wound healing properties.

Conclusion

Agaricus blazei Murrill contains numerous bioactive components that function as biological response modifiers, activating immune systems for multiple defensive functions. While polysaccharides demonstrate anticancer, antiviral, and immunomodulatory effects, β-glucans show antihyperglycemic, antihypertriglyceridemic, and antiarteriosclerotic activities. However, further careful clinical studies are needed to fully determine real clinical benefits and identify specific compounds responsible for therapeutic effects.
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