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The Health-Promoting Properties and Clinical Applications of Rice Bran Arabinoxylan Modified with Shiitake Mushroom Enzyme—A Narrative Review

Summary

Rice bran arabinoxylan compound (RBAC) is a natural supplement made from rice bran modified with shiitake mushroom enzymes. This compound has shown remarkable potential in supporting human health through its ability to enhance immune function and fight inflammation. Impact on everyday life: • Can be taken as a daily supplement to support immune system function and overall health • May help reduce side effects of cancer treatments while improving treatment outcomes • Could help prevent common colds, especially in older adults • Shows promise in managing chronic conditions like irritable bowel syndrome and liver problems • Offers a safe, natural option for supporting health with no known side effects at typical doses

Background

Rice bran arabinoxylan compound (RBAC) is derived from defatted rice bran hydrolyzed with Lentinus edodes mycelial enzyme. It has been marketed as a functional food and nutraceutical with health-promoting properties. Rice bran is the rough brown layer between the outer husk and endosperm of rice, constituting about 8% of the grain and containing numerous nutrients and bioactive compounds.

Objective

To comprehensively review the available research on the potential benefits of RBAC for cancer and other health conditions based on the available literature, examining its health-promoting properties and clinical applications.

Results

Research demonstrates RBAC acts as a potent immunomodulator with anti-inflammatory, antioxidant, and anti-angiogenic properties. Clinical studies show benefits for cancer therapy, HIV infection, diabetes, irritable bowel syndrome, liver diseases, chronic fatigue syndrome, and common cold prevention. RBAC is safe to consume with no known side effects at typical dosages of 2-3 g/day.

Conclusion

RBAC shows promise as a functional food and nutraceutical with multiple health-promoting properties. Strong evidence supports its use as a complementary therapy in cancer treatment. While initial research suggests benefits for various other health conditions, more research is needed to fully establish its mechanisms of action and clinical applications beyond cancer therapy.
  • Published in:Molecules,
  • Study Type:Review,
  • Source: 10.3390/molecules26092539
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