Profiling and Quantifying Differential Gene Transcription Provide Insights into Ganoderic Acid Biosynthesis in Ganoderma lucidum in Response to Methyl Jasmonate

This research examined how a plant hormone called methyl jasmonate affects the production of beneficial compounds called ganoderic acids in the medicinal mushroom Ganoderma lucidum. The study identified genes that are activated or suppressed when the mushroom is treated with this hormone, helping to understand how the mushroom produces these therapeutic compounds. Impacts on everyday life: • Provides insights that could lead to improved production of natural medicines from mushrooms • Advances understanding of how medicinal mushrooms make beneficial compounds • Could help make therapeutic mushroom extracts more affordable and accessible • Demonstrates new ways to enhance production of natural pharmaceutical compounds • Contributes to development of more effective mushroom-based supplements