Positive interaction between melatonin and methyl jasmonate enhances Fusarium wilt resistance in Citrullus lanatus
- Author: mycolabadmin
- 5/1/2025
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Summary
This research shows that two plant compounds, melatonin and methyl jasmonate, work together to protect watermelon plants from a devastating fungal disease called Fusarium wilt. When applied to plant roots at specific concentrations, these compounds activate the plant’s natural defense mechanisms and directly slow down fungal growth. Importantly, the two compounds enhance each other’s effects, creating a protective cycle that makes the plant significantly more resistant to infection, offering a natural alternative to chemical pesticides.
Background
Fusarium wilt caused by Fusarium oxysporum is a devastating soil-borne fungal disease affecting numerous crops including watermelon. Melatonin has emerged as a potential enhancer of plant resistance, but the underlying mechanisms remain unclear. This study investigates the synergistic interaction between melatonin and methyl jasmonate in combating Fusarium wilt.
Objective
To elucidate the mechanisms by which exogenous melatonin and methyl jasmonate (MeJA) enhance watermelon resistance against Fusarium oxysporum f. sp. Niveum race 2 (FON2) and to determine if they form a reciprocal positive regulatory loop.
Results
Optimal melatonin (10 μM) and MeJA (1 μM) concentrations induced dose-dependent FON2 resistance. Melatonin upregulated MeJA synthesis genes and increased MeJA content, while MeJA reciprocally promoted melatonin accumulation through ClCOMT1 upregulation. Both compounds enhanced polyphenol oxidase, phenylalanine ammonia lyase activities and lignin content, establishing a positive regulatory loop against FON2.
Conclusion
Melatonin and MeJA form a reciprocal positive regulatory loop that synergistically enhances watermelon resistance against Fusarium wilt through direct mycelial growth inhibition and activation of defense mechanisms including enzymatic activities and lignin accumulation, offering sustainable alternatives to pesticide-based management.
- Published in:Frontiers in Plant Science,
- Study Type:Experimental Study,
- Source: PMID: 40376169, DOI: 10.3389/fpls.2025.1508852