Nosocomial Diarrhea Distribution by Cryptosporidium in Isfahan

Summary

Researchers tested 217 patients who developed diarrhea in a hospital in Isfahan, Iran to see if a parasite called Cryptosporidium was responsible. Using advanced DNA testing, they found the parasite in only 2 out of 217 patients (less than 1%). This suggests that while this parasite can spread in hospitals, it is not a major cause of diarrhea in this particular hospital, which likely has good hygiene practices.

Background

Cryptosporidium spp. is a parasite causing cryptosporidiosis, a diarrheal disease transmitted through contaminated water, food, and feces. Nosocomial diarrhea is diarrhea occurring more than 72 hours after hospital admission. This study investigates the distribution of nosocomial diarrhea caused by Cryptosporidium in Isfahan, central Iran.

Objective

To determine the prevalence and distribution of Cryptosporidium spp. in patients developing diarrhea within 48-72 hours of hospital admission at Al-Zahra Hospital in Isfahan.

Results

No Cryptosporidium oocysts were detected by microscopy. Nested PCR identified Cryptosporidium spp. in 2 of 217 samples (0.92% prevalence). Results suggest uncommon occurrence of nosocomial diarrhea specifically caused by Cryptosporidium.

Conclusion

The distribution of nosocomial diarrhea caused by Cryptosporidium is uncommon in this hospital setting. Healthcare settings can still be potential sources of transmission for cryptosporidiosis and other infectious diseases. Understanding nosocomial diarrhea epidemiology is necessary for proper hygiene management in developing countries.
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