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Modulation of Abortiporus biennis Response to Oxidative Stress by Light as a New Eco-Friendly Approach with a Biotechnological Perspective

Summary

Researchers studied how different colored lights and a chemical called menadione affect a white rot fungus called Abortiporus biennis. They found that combining red light with menadione significantly increased the fungus’s metabolic activity and production of useful compounds like laccase, an enzyme with industrial and medical applications. The study shows that using simple, eco-friendly stressors like colored light could help boost the fungus’s beneficial properties for practical use.

Background

White rot fungi like Abortiporus biennis possess sophisticated mechanisms to respond to oxidative stress and produce bioactive compounds. The fungus can sense and respond to different light wavelengths through photoreceptor proteins. Understanding how light and chemical stressors modulate fungal metabolism is important for biotechnological applications.

Objective

This study aimed to comprehensively explore how oxidative stress induced by menadione (chemical stressor) and light at various wavelengths (physical stressor) affect the metabolism and biochemical markers of the white rot fungus A. biennis. The goal was to determine if these eco-friendly stressors could synergistically improve the fungus’s biotechnological potential.

Results

Menadione and light significantly altered A. biennis metabolic profiles, with the fungus preferring polymer utilization. Green and red light had notable effects on metabolic activity. Menadione strongly stimulated laccase activity, while inhibiting catalase and superoxide dismutase activities. The highest antioxidative effect was observed on day 5 in green light. Superoxide levels were highest in darkness and red light conditions.

Conclusion

The response of A. biennis to combined light and menadione-induced oxidative stress is complex and multidirectional, with synergistic effects observed particularly with red light and menadione on metabolic activity and phenolic compound concentration. These findings provide a basis for efficient, eco-friendly improvements of the industrial and medicinal applications of A. biennis.
  • Published in:International Journal of Molecular Sciences,
  • Study Type:Experimental Research,
  • Source: PMID: 40564949, DOI: 10.3390/ijms26125482
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