Ganoderma lucidum Stimulates Autophagy-Dependent Longevity Pathways in Caenorhabditis elegans and Human Cells

This research shows that the medicinal mushroom Ganoderma lucidum (reishi) can extend lifespan by activating cellular cleaning and stress resistance mechanisms. The study found that compounds from this mushroom work similarly to caloric restriction, a known way to extend lifespan, but without requiring dietary changes. Impacts on everyday life: – Suggests reishi mushroom supplements might help promote healthy aging – Identifies natural compounds that could mimic benefits of caloric restriction without strict dieting – Provides scientific support for traditional use of reishi as a health tonic – Opens possibilities for developing new anti-aging supplements – Demonstrates how traditional medicines can have measurable biological effects