MYCOLab Ai Logo - gold and army green

Evidence-Based Nutraceuticals Derived from Antrodia cinnamomea

Summary

Antrodia cinnamomea, a mushroom from Taiwan traditionally used for health, contains many beneficial compounds that fight inflammation, tumors, and oxidative stress. Research shows it can help with cancer, liver disease, diabetes, and high blood pressure. The mushroom can be grown in laboratories and its active compounds extracted using various modern techniques, making it promising for health supplements and medicines.

Background

Antrodia cinnamomea is a medicinal and edible mushroom endemic to Taiwan traditionally used as a health tonic. Recent studies have identified diverse bioactive compounds including benzenoids, maleic and succinic acids, ubiquinone, triterpenoids, and polysaccharides with various pharmacological properties.

Objective

This review evaluates recent advancements in the cultivation, extraction, and characterization of bioactive compounds from A. cinnamomea, with particular focus on submerged and solid-state fermentation methods. The review aims to provide a comprehensive framework for promoting efficient and evidence-based utilization of A. cinnamomea in therapeutic strategies and health innovations.

Results

A. cinnamomea exhibits antibacterial, antitumor, anti-inflammation, hepatoprotection, hypoglycemia, and antioxidant activities through its bioactive compounds. Key findings include antcin K and dehydroeburicoic acid showing potent α-glucosidase inhibitory activity, and clinical trials demonstrating immunomodulatory, hepatoprotective, antihypertensive, and cholesterol-lowering effects.

Conclusion

A. cinnamomea demonstrates significant therapeutic potential across multiple health domains with broad applications in health supplements and functional foods. However, standardization of quality control and development of environmentally friendly extraction methods remain critical challenges for future commercial development.
  • Published in:Foods,
  • Study Type:Review,
  • Source: PMID: 40238365
Scroll to Top