Electrospinning Enables Opportunity for Green and Effective Antibacterial Coatings of Medical Devices
- Author: mycolabadmin
- 7/6/2025
- View Source
Summary
Scientists have developed a greener way to coat medical devices like wound dressings and catheters with antibacterial materials using electrospun fibers. These tiny fibers are made from natural, renewable materials and release antimicrobial agents slowly and effectively to prevent infections. Unlike traditional antibiotics that can create resistance, these coatings use multiple attack methods against bacteria, making them harder for microbes to develop resistance against.
Background
Antimicrobial resistance and environmental concerns associated with conventional antibacterial agents have prompted research into sustainable alternatives. Biopolymer-based nanofibers offer high surface-to-volume ratios and tunable porosity, making them suitable for delivering antimicrobial agents and modifying medical device surfaces.
Objective
This review critically explores recent advances in electrospun fibers enhanced with natural antimicrobial agents as eco-friendly surface coatings for medical devices. The review examines mechanisms of antibacterial action, factors affecting efficacy, and comparisons with conventional agents.
Results
The review demonstrates that electrospun fibers employ multiple antibacterial strategies including sustained drug release and physical interactions with bacterial cells, reducing resistance likelihood. Applications include implants, wound dressings, surgical textiles, and urinary devices with demonstrated effectiveness in combating antibiotic-resistant pathogens.
Conclusion
Green electrospinning using biopolymers and eco-friendly solvents provides sustainable antibacterial coatings superior to conventional agents. These technologies show promise for next-generation healthcare solutions addressing both antimicrobial resistance and environmental sustainability.
- Published in:Journal of Functional Biomaterials,
- Study Type:Review,
- Source: PMC12295855, 40710463