MYCOLab Ai Logo - gold and army green

Biological Characterization and Antimicrobial Bioactives of Mycelium Extracts from Medicinal Mushrooms Phellinus linteus and Pleurotus albidus

Summary

This research investigated how extracts from two medicinal mushrooms could fight against harmful bacteria. Scientists found that these mushroom extracts contain natural compounds that can effectively kill or inhibit various types of bacteria that cause infections. This discovery could lead to new natural antibiotics and health supplements. Impacts on everyday life: • Could lead to new natural antibiotics to fight bacterial infections • May result in development of natural health supplements • Provides alternative treatment options for antibiotic-resistant infections • Could reduce reliance on synthetic pharmaceutical drugs • Demonstrates the potential of mushrooms as natural medicine sources

Background

Bioactivity is defined as the intrinsic property of compounds that enables their participation in specific biological reactions. Medicinal mushrooms are known to contain bioactive compounds with potential therapeutic applications.

Objective

This study aimed to evaluate the antimicrobial capacity and to separate and characterize bioactives from aqueous and hydroalcoholic extracts obtained from the mycelium of medicinal mushrooms Pleurotus albidus and Phellinus linteus.

Results

P. albidus extracts showed better activity against Bacillus strains, while Ph. linteus extracts demonstrated greater effectiveness against S. aureus and P. aeruginosa. Aqueous extraction proved optimal for obtaining bioactive compounds from P. albidus, whereas 30% hydroalcoholic extraction was more effective for Ph. linteus. The analysis identified key compounds including glutathione oxidase, leucovorin, and riboflavin.

Conclusion

P. albidus and Ph. linteus show potential as sources of bioactive molecules that could be used in the development of novel drugs or nutraceuticals, potentially contributing to improvements in public health.
  • Published in:International Journal of Medical Mushrooms,
  • Study Type:Laboratory Research,
  • Source: PMID: 35695637
Scroll to Top