Antioxidation and Hepatoprotection of Selenium Mycelium Polysaccharides Against Alcoholic Liver Diseases from the Cultivated Morel Mushroom Morchella esculenta
- Author: mycolabadmin
- 2024-01-01
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Summary
Scientists have discovered that compounds from morel mushrooms enriched with selenium can help protect the liver from alcohol-related damage. This research shows how natural mushroom extracts could potentially be used to treat liver diseases caused by alcohol consumption.
Impacts on everyday life:
• Offers a potential natural treatment option for people with alcohol-related liver problems
• Demonstrates the health benefits of consuming medicinal mushrooms
• Shows promise for developing new liver-protective supplements
• Highlights the importance of natural antioxidants in maintaining liver health
• Suggests new ways to enhance the medicinal properties of edible mushrooms
Background
The liver is considered the most important metabolic and detoxification organ in the body. Morchella esculenta is a rare edible fungus belonging to Ascomycetes that has been reported to have numerous bioactive properties.
Objective
This study aimed to investigate and confirm the potential antioxidant activities of selenium mycelium polysaccharides (Se-MIP) extracted from M. esculenta against alcoholic liver diseases (ALD) in mice.
Results
The research found that Se-MIP demonstrated significant antioxidant capabilities at a selenium concentration of 25 μg/mL in vitro. In vivo studies with mice showed that Se-MIP effectively improved antioxidant activities and reduced hepatic dysfunction related to alcoholic liver disease.
Conclusion
The study concluded that selenium mycelium polysaccharides (Se-MIP) from M. esculenta show promise as a potential therapeutic agent for treating alcoholic liver diseases and related complications, warranting further clinical investigation.
- Published in:International Journal of Medicinal Mushrooms,
- Study Type:Experimental Study,
- Source: 10.1615/IntJMedMushrooms.2023051288