Antimicrobial Activity of Extracts of the Oyster Culinary Medicinal Mushroom Pleurotus ostreatus and Identification of a New Antimicrobial Compound
- Author: mycolabadmin
- 2015-06-01
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Summary
Scientists discovered that the common oyster mushroom (Pleurotus ostreatus) contains powerful antimicrobial compounds that can fight both harmful bacteria and fungi. They identified a new compound that could potentially be developed into natural medicines. Impact on everyday life:
• Could lead to new natural antibiotics for treating infections
• Demonstrates additional health benefits of including oyster mushrooms in diet
• Shows potential for developing natural food preservatives
• Provides evidence for traditional medicinal uses of mushrooms
• Opens possibilities for eco-friendly antimicrobial treatments
Background
Pleurotus ostreatus is an edible mushroom known for both its culinary use and medicinal properties. Understanding its antimicrobial properties could lead to new therapeutic applications.
Objective
To evaluate the antimicrobial activity of various extracts from P. ostreatus against fungi and bacteria, and to identify and characterize the active antimicrobial compound responsible for these effects.
Results
Water extracts from fruiting bodies showed the strongest antimicrobial activity, particularly against Candida albicans, Cryptococcus humicola, Trichosporon cutaneum, Staphylococcus aureus, and Escherichia coli. The active compound was identified as 3-(2-aminopheny1thio)-3-hydroxypropanoic acid, with minimum inhibitory concentrations of 30 µg/mL for fungi and 20 µg/mL for bacteria.
Conclusion
The study successfully identified a novel antimicrobial compound from P. ostreatus water extracts, with significant activity against both fungi and bacteria. Water extracts proved more effective than alcohol-based extracts, particularly those from fruiting bodies.
- Published in:International Journal of Medical Mushrooms,
- Study Type:Laboratory Research,
- Source: 10.1615/intjmedmushrooms.v17.i6.80