A Novel Gammapartitivirus That Causes Changes in Fungal Development and Multi-Stress Tolerance to Important Medicinal Fungus Cordyceps chanhua
- Author: mycolabadmin
- 2022-12-16
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Summary
This research discovered a new virus that infects the medicinal mushroom Cordyceps chanhua, which has been used in traditional Chinese medicine for 1500 years. While the virus slows down the mushroom’s growth and makes it more sensitive to stress, it significantly increases the production of spores and fruiting bodies – the parts used for medicine. This discovery could lead to better ways of growing this valuable medicinal mushroom.
Impacts on everyday life:
– Could lead to more efficient production of medicinal mushroom products
– May help reduce costs of traditional medicine supplements
– Provides new understanding of how viruses can be used to enhance mushroom cultivation
– Could contribute to development of improved medicinal mushroom strains
– May help make traditional Chinese medicine more accessible to general public
Background
Cicada flower (Cordyceps chanhua) is an important Chinese medicinal mushroom with a 1500-year history of use. It has been used to treat various conditions including malaria, cancer, diabetes, and kidney diseases. While mycoviruses are widely distributed in fungi and can affect their hosts, the effects of mycovirus infection on C. chanhua development and stress tolerance were previously unknown.
Objective
To characterize a novel mycovirus (CchPV1) from C. chanhua isolate RCEF5997 and analyze its effects on fungal development and stress tolerance through horizontal transmission experiments.
Results
The study identified CchPV1 as a novel member of the Gammapartitivirus genus with two genome segments. Virus infection slowed host growth rate by 7-20% but increased conidiation by 91% and fruiting body production by 64%. The virus-infected strain showed reduced tolerance to various stresses including osmotic, oxidative, UV radiation and heat stress.
Conclusion
This is the first report of a partitivirus from C. chanhua. While CchPV1 infection reduced growth rate and stress tolerance, it significantly enhanced reproductive capabilities through increased conidiation and fruiting body formation. This finding provides a potential new strategy for improving production of medicinal C. chanhua fruiting bodies.
- Published in:Journal of Fungi,
- Study Type:Laboratory Research,
- Source: 10.3390/jof8121309