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A case report of Saksenaea vasiformis mucormycosis infection of a lower segment caesarean section wound

Summary

A young woman developed a rare fungal infection (mucormycosis) in her caesarean section wound seven days after surgery. Despite initial antibiotic treatment, she required multiple surgical debridement procedures combined with antifungal medications to eliminate the infection. The surgical team successfully reconstructed her abdominal wall using specialized mesh and skin grafting techniques, resulting in complete healing.

Background

Mucormycosis is a rare and aggressive fungal infection that predominantly affects immunocompromised patients. Only two previous case reports of mucormycosis infections following caesarean section have been published. This case describes an exceptionally rare occurrence in a developed country.

Objective

To report a case of Saksenaea vasiformis mucormycosis infection in a lower segment caesarean section wound and describe the complex multidisciplinary management required for treatment and reconstruction.

Results

Histological analysis identified fungal hyphae with characteristic 90-degree branching and angioinvasion, confirmed as Saksenaea vasiformis. Treatment with liposomal amphotericin B and posaconazole combined with radical debridement successfully resolved the infection. Reconstruction was performed using Phasix mesh, biodegradable temporizing matrix, and split-thickness skin grafting.

Conclusion

This case highlights the exceptionally rare diagnosis of mucormycosis in a caesarean section wound and demonstrates that aggressive antifungal treatment combined with radical surgical debridement is essential for successful outcome. Complex reconstruction using modern biomaterials can be safely performed in infected settings.
  • Published in:International Journal of Surgery Case Reports,
  • Study Type:Case Report,
  • Source: PMID: 40939469, DOI: 10.1016/j.ijscr.2025.111923
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