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A Case Report of Candidiasis Cellulitis in Long-Term Corticosteroid Use

Summary

A 54-year-old man developed a serious hand infection caused by Candida albicans, a yeast that normally lives harmlessly on human skin. The infection occurred because he had been taking large doses of corticosteroid injections for 15 years to help with breathing problems, which weakened his immune system. Doctors drained the infected area and treated him with antifungal medication, and he recovered completely, highlighting the importance of recognizing fungal infections in patients on long-term steroid therapy.

Background

Candida albicans is typically a harmless commensal organism but can become pathogenic in immunocompromised individuals. Prolonged corticosteroid use significantly increases the risk of opportunistic fungal infections. This case highlights the importance of considering fungal etiologies in vulnerable populations.

Objective

To present a case of cutaneous candidiasis cellulitis in a patient with prolonged betamethasone use and demonstrate the clinical presentation, diagnosis, and management of this rare infection. The report emphasizes the need for heightened clinical suspicion of fungal infections in immunocompromised patients.

Results

Direct smear showed budding yeast cells and culture confirmed Candida albicans infection. Blood cultures remained negative on two occasions. The patient responded well to oral fluconazole 200 mg every 12 hours after initial vancomycin discontinuation. Complete resolution of symptoms was achieved within 2 weeks of antifungal therapy.

Conclusion

This case highlights the significant risk of C. albicans infections in immunocompromised patients receiving prolonged glucocorticoid therapy. Early diagnosis through culture and prompt antifungal treatment with fluconazole are crucial for optimal outcomes. Healthcare providers must maintain high clinical suspicion for opportunistic fungal pathogens in at-risk populations.
  • Published in:Case Reports in Medicine,
  • Study Type:Case Report,
  • Source: PMID: 41064498, DOI: 10.1155/carm/6140044
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