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A brief overview of the medicinal and nutraceutical importance of Inonotus obliquus (chaga) mushrooms

Summary

Chaga mushrooms are a traditional medicine used for centuries in Eastern Europe and Asia that contains powerful compounds beneficial for health. These mushrooms have been shown to help fight cancer, reduce inflammation, boost immunity, and protect cells from damage through their natural antioxidants. Modern scientific research is confirming what traditional healers have known for centuries about this remarkable fungus, making it an increasingly popular natural supplement for health and wellness.

Background

Chaga mushrooms (Inonotus obliquus) are white rot fungi inhabiting birch trees in colder northern regions, with a long history of use as folk remedies in Western Siberia and Russia. These mushrooms contain diverse bioactive constituents including polysaccharides, triterpenoids, phenolic compounds, and melanins.

Objective

To provide an extensive exploration of Chaga mushrooms, focusing on their phytochemical composition, health-promoting attributes, and mechanisms of action. The review aims to highlight Chaga’s significance in the medicinal sector and its potential role in diverse health benefits.

Results

The review identified numerous bioactive compounds in Chaga with remarkable anticancer, antioxidant, anti-diabetic, anti-inflammatory, antimicrobial, and immunomodulating properties. Key compounds include polysaccharides, triterpenoids (betulin, betulinic acid, inotodiol), phenolic compounds, melanin, and ergosterol peroxide, each contributing to various therapeutic effects.

Conclusion

Chaga mushrooms hold significant promise as a source of natural health interventions with diverse pharmacological potential. The review emphasizes the need for continued investigation into Chaga’s bioactive compounds and their mechanisms of action to fully comprehend their therapeutic applications and integrate them into mainstream medicine.
  • Published in:Heliyon,
  • Study Type:Literature Review,
  • Source: PMID: 39170453, DOI: 10.1016/j.heliyon.2024.e35638
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