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A Case Report of Candidiasis Cellulitis in Long-Term Corticosteroid Use

Summary

A 54-year-old man developed a serious skin infection on his hand caused by Candida, a normally harmless fungus, because he had been taking corticosteroid injections for 15 years for breathing problems. Despite antibiotic treatment, the swelling and pain continued. Doctors discovered it was a fungal infection through lab tests and treated it with antifungal medication (fluconazole) after draining the infection, which completely healed within two weeks.

Background

Candida albicans is typically a benign commensal organism but can become pathogenic in immunocompromised individuals. Prolonged corticosteroid use significantly increases the risk of opportunistic fungal infections. This case presents a rare occurrence of cutaneous candidiasis cellulitis in a patient on long-term betamethasone therapy.

Objective

To report and discuss a case of Candida albicans cutaneous abscess with cellulitis in a patient receiving prolonged corticosteroid therapy. The report aims to highlight the importance of considering fungal etiologies in immunocompromised patients with nonresolving cellulitis.

Results

Culture of the abscess contents confirmed Candida albicans infection, while blood cultures remained negative. Direct smear showed budding yeast cells. The patient responded favorably to oral fluconazole 200 mg twice daily, with complete resolution of symptoms within two weeks.

Conclusion

This case demonstrates the opportunistic potential of Candida albicans in immunocompromised patients, particularly those receiving prolonged corticosteroid therapy. Early diagnosis through culture and prompt antifungal treatment are crucial for positive outcomes. Healthcare providers must maintain heightened clinical suspicion for fungal infections in at-risk populations.
  • Published in:Case Reports in Medicine,
  • Study Type:Case Report,
  • Source: PMID: 41064498, DOI: 10.1155/carm/6140044
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