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Draft whole genome sequence of Alternaria alternata strain P02PL2, an endophytic fungal species isolated from Sclerocarya birrea

Summary

Scientists sequenced the complete genetic blueprint of a beneficial fungus called Alternaria alternata that lives inside African marula tree leaves. This fungus produces many different bioactive compounds with potential medical applications. The genetic information is now publicly available for researchers to study how this fungus makes these useful compounds and develop new treatments.

Background

Alternaria alternata are filamentous Ascomycetes that can function as plant pathogens, facultative parasites, saprophytes, or endophytes. The availability of whole genome sequences enables optimal exploitation of bioactive compounds produced by these fungal species. This study reports the draft genome sequence of A. alternata P02PL2 isolated from Sclerocarya birrea leaves.

Objective

To generate and characterize the draft whole genome sequence of the endophytic fungal species Alternaria alternata strain P02PL2 isolated from Sclerocarya birrea, and to assess its biotechnological potential through genome analysis.

Results

The assembled genome size was 32.0 Mb with 50.56% GC content and an N50 scaffold of 721,337 bp. BUSCO completeness scores were 93% against Sordariomycetes and 92% against Ascomycetes. The genome contained 9,614 RNA genes (9,521 mRNA and 93 tRNA) and 6,737 protein-coding sequences, revealing 833 biosynthetic pathways and 1,016 catalytic activities.

Conclusion

The draft genome sequence of A. alternata P02PL2 is now publicly available and demonstrates this isolate is rich in pathways with biotechnological applications. This genomic resource will facilitate the exploitation of bioactive compounds produced by this endophytic fungal species.
  • Published in:Microbiology Resource Announcements,
  • Study Type:Genome Sequencing Study,
  • Source: 10.1128/mra.00865-24, PMID: 39964187
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