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Candida tropicalis Fungal Keratitis: A Case Report and Literature Review

Summary

A 66-year-old patient with a long history of corneal problems developed a serious eye infection caused by a fungus called Candida tropicalis. Doctors identified the infection through laboratory tests and treated it successfully with antifungal medications. This is the first documented case of this particular fungal infection in Morocco and highlights the importance of testing for fungal infections in patients with existing eye problems.

Background

Fungal keratitis, or keratomycosis, is a serious corneal infection caused by fungi. While Candida albicans is the most common causative agent, emerging Candida species including C. tropicalis have been identified as rare causes of ocular infections.

Objective

To report the first case of Candida tropicalis corneal abscess diagnosed in Morocco and review the literature on this rare fungal infection in ophthalmology.

Results

Culture revealed creamy whitish colonies identified as Candida tropicalis through biochemical assays. Antifungal susceptibility testing showed sensitivity to voriconazole, intermediate sensitivity to fluconazole, and resistance to flucytosine. The patient responded well to antifungal treatment with improved local condition and visual acuity.

Conclusion

This case highlights the importance of considering fungal keratitis in diagnosis, particularly in immunocompromised patients or those with existing corneal pathology. Early diagnosis and appropriate antifungal therapy are essential to prevent complications and preserve vision. Multidisciplinary collaboration between ophthalmologists and microbiologists is critical for optimal patient outcomes.
  • Published in:Cureus,
  • Study Type:Case Report and Literature Review,
  • Source: PMID: 39036143, DOI: 10.7759/cureus.62682
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