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The Role of Nitric Oxide in the Growth and Development of Schizophyllum commune Under Anaerobic Conditions

Summary

This study shows that nitric oxide, a chemical messenger, plays an important role in helping a wood-decay fungus called Schizophyllum commune grow and reproduce in environments without oxygen. When nitric oxide levels are boosted, the fungus grows better and can even start forming fruiting bodies (mushrooms) under low-oxygen conditions. These findings could help scientists understand how fungi survive and thrive in extreme environments like deep ocean sediments.

Background

Nitric oxide (NO) is a signaling molecule with diverse roles in biological processes. While NO’s effects have been studied in various fungi under aerobic conditions, its specific effects on fungal growth and development under anaerobic conditions remain largely unexplored.

Objective

This study investigates how nitric oxide influences the growth and development of Schizophyllum commune 20R-7-F01 under anaerobic environments, examining mycelial growth, basidiospore germination, and fruiting body formation.

Results

Endogenous NO levels increased during mycelial growth and basidiospore germination. cPTIO treatment inhibited mycelial growth and delayed spore germination with reduced germination gene expression. Exogenous NO supplementation accelerated mycelial growth and promoted primordium formation, upregulating fruiting body development genes.

Conclusion

NO functions as a critical signaling molecule regulating multiple stages of S. commune development under anaerobic conditions, including mycelial growth, spore germination, and early fruiting body formation, suggesting its importance in fungal adaptation to low-oxygen environments.
  • Published in:Microorganisms,
  • Study Type:Experimental Study,
  • Source: PMID: 40284723
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