Copper and Zinc-Enriched Mycelium of Agaricus Blazei Murrill: Bioaccumulation and Bioavailability
- Author: mycolabadmin
- 2007-03-01
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Summary
This research explored how mushroom mycelium can be enriched with essential minerals like copper and zinc to create natural nutritional supplements. The study found that the mushroom tissue could effectively accumulate these minerals and make them available for human absorption when consumed. This has important implications for developing natural mineral supplements.
Impacts on everyday life:
• Provides a natural alternative to synthetic mineral supplements
• Offers a new way to address mineral deficiencies through food
• Demonstrates how mushrooms can be enhanced to provide better nutrition
• Shows potential for developing more effective dietary supplements
• Could lead to more sustainable methods of mineral supplementation
Background
Agaricus blazei is an edible mushroom known for its medicinal properties. Research was needed to evaluate its potential as a dietary supplement vehicle for essential minerals like copper and zinc through mycelium enrichment.
Objective
To study the accumulation and potential bioavailability of copper (Cu) and zinc (Zn) in Agaricus blazei mycelium when grown in the presence of these metals, with the goal of developing organic combinations useful as food dietary supplements.
Results
At 400 ppm exposure, the mycelium accumulated 449 times the basal content of copper and 163 times the basal content of zinc. When using non-mycotoxic concentrations (100 and 200 ppm), about 90% of accumulated metals were found in the available non-residual fraction, performing similar to or better than commercial supplements. The solubility in simulated digestive fluids was 30-34% for copper and 18-33% for zinc, providing 60-98% and 9-11% of the recommended daily intake respectively from just 1g of mycelium.
Conclusion
A. blazei mycelium shows significant potential as a vehicle for copper and zinc supplementation, demonstrating both high accumulation capacity and good bioavailability of these minerals when subjected to simulated digestion conditions.
- Published in:Journal of Medicinal Food,
- Study Type:Laboratory Research,
- Source: 10.1089/jmf.2005.064