MYCOLab Ai Logo - gold and army green

A Resequencing-Based Ultradense Genetic Map of Hericium erinaceus for Anchoring Genome Sequences and Identifying Genetic Loci Associated with Monokaryon Growth

Summary

This research created the first detailed genetic map of lion’s mane mushroom (Hericium erinaceus), providing a crucial tool for mushroom breeding and improvement. The study helps scientists better understand how different genetic regions influence mushroom growth and development. Impacts on everyday life: – Enables development of improved mushroom varieties with better growth and yields – Helps create more efficient cultivation methods for medicinal mushrooms – Supports development of mushrooms with enhanced health benefits – Could lead to more affordable and accessible medicinal mushroom products – Advances sustainable food and medicine production methods

Background

Hericium erinaceus (lion’s mane mushroom) has attracted significant interest due to its health-promoting properties and bioactive compounds. However, breeding of elite cultivars is hindered by limited genetic and molecular tools. Current understanding of H. erinaceus molecular biology and genetics remains limited, preventing genetic improvement of mushroom yield and quality.

Objective

To construct the first high-resolution genetic map of H. erinaceus using resequencing analysis of 127 F1 single-spore isolates, and to detect quantitative trait loci (QTLs) for monokaryon growth.

Results

An ultradense genetic map consisting of 1,174 bins (including 37,082 SNPs) was generated, covering 1,096.5 cM with average bin spacing of 0.95 cM. High collinearity between the genetic map and genome assembly was revealed. Four QTLs for monokaryon growth were identified, with one QTL (mgr1) contributing 12.1% of growth variations located near the mating type A loci.

Conclusion

The first high-resolution genetic map of H. erinaceus was successfully constructed and validated through genome assembly alignment and QTL mapping. This newly developed genetic map provides a valuable resource for future genetic, genomic and breeding studies of H. erinaceus.
  • Published in:Frontiers in Microbiology,
  • Study Type:Genetic Mapping Study,
  • Source: 10.3389/fmicb.2019.03129
Scroll to Top