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Mushrooms-Rich Preparations on Wound Healing: From Nutritional to Medicinal Attributes

Summary

This research examines how mushrooms can help in wound healing while also providing important nutritional benefits. Mushrooms contain special compounds that help wounds heal faster and better by supporting the immune system and reducing inflammation. The study shows that certain mushrooms like Reishi and Lion’s Mane are particularly effective for wound treatment. Impacts on everyday life: – Mushrooms can be used as natural alternatives for wound treatment – Regular consumption of edible mushrooms provides important nutrients and health benefits – Mushroom-based products could lead to new wound healing medications and skincare products – Mushrooms offer a sustainable and affordable source of both food and medicine – People with chronic wounds or slow healing conditions may benefit from mushroom-based treatments

Background

Mushrooms have played a significant role in human diet as both functional food and nutraceutical resources. They combine umami flavor with protein, vitamins, minerals and carbohydrates, making them an affordable food source in many countries. Additionally, mushrooms contain diverse bioactive metabolites that show promise in preventing and treating various human health conditions.

Objective

This review aims to provide key insights on mushrooms’ nutritional value and composition, ethnobiology and ethnopharmacology, and wound healing potential, with particular focus on understanding their mechanisms of action in wound repair processes.

Results

The review found that mushrooms contain significant amounts of protein (19-35%), carbohydrates (50-65%), essential amino acids, vitamins (especially B and D), minerals, and bioactive compounds like β-glucans and polysaccharides. Multiple studies demonstrated mushrooms’ wound healing properties through mechanisms including immune cell stimulation, collagen synthesis promotion, anti-inflammatory effects, and antioxidant activity. Key species like Ganoderma lucidum, Hericium erinaceus, and Sparassis crispa showed particular promise in accelerating wound healing.

Conclusion

Mushrooms represent a valuable source of both nutritional and medicinal compounds, with demonstrated wound healing properties linked to their rich content of polysaccharides and phenolic compounds. While some species show significant therapeutic potential, further research is needed to fully assess bioactive compounds and their healing mechanisms. The use of mushroom components in cosmetics presents a promising area for future development.
  • Published in:Frontiers in Pharmacology,
  • Study Type:Review,
  • Source: 10.3389/fphar.2020.567518
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