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Multidisciplinary Integrative Medicine Approach for Cancer Patients: A Multicenter Retrospective Study

Summary

This study shows that when cancer patients use complementary treatments like mushroom supplements, vitamins, and probiotics alongside their cancer medications under doctor supervision, they experience fewer side effects and better quality of life. Almost 93% of patients had no side effects from these supplements, and many reported less fatigue and better overall wellness. The key finding is that patients should work with their medical team rather than self-prescribing these treatments to avoid dangerous interactions.

Background

Complementary integrative medicine (CIM) is commonly used by cancer patients to improve quality of life and support immune function. However, many patients self-prescribe CIM without medical supervision, risking interactions with anticancer treatments. This study evaluates a supervised, multidisciplinary approach to CIM in cancer patients.

Objective

To demonstrate the feasibility of combining CIM with anticancer treatments in a multidisciplinary approach to improve quality of life, reduce adverse events, and ensure safety in cancer patients. Secondary objectives included investigating the impact on survival outcomes.

Results

No adverse events occurred in 92.6% of patients, with only 7.4% experiencing gastrointestinal or liver toxicity. Main benefits included improved fatigue and quality of life (44.4% of patients), particularly with combined U-CARE and polytherapy approaches. Best response to oncological treatment showed 20.4% complete response and 38.7% partial response rates.

Conclusion

The multidisciplinary CIM approach demonstrated feasibility and safety when supervised by expert physicians, improving quality of life and reducing anticancer treatment toxicity. This evidence-based, patient-centered approach aligns with EU cancer control strategies and avoids risks of harmful self-prescription.
  • Published in:Nutrients,
  • Study Type:Multicenter Retrospective Study,
  • Source: PMID: 40290037, DOI: 10.3390/nu17061012
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