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Freeze-Dried Probiotic Fermented Camel Milk Enriched with Ajwa Date Pulp: Evaluation of Functional Properties, Probiotic Viability, and In Vitro Antidiabetic and Anticancer Activities

Summary

Researchers created a powdered functional food by combining fermented camel milk with Ajwa date pulp and probiotics. The product showed promise in helping manage blood sugar levels and fighting cancer cells in laboratory tests. Adding date pulp improved the powder’s ability to mix with water and helped beneficial bacteria survive digestion. This combination of camel milk and dates offers a potential new functional food option for people looking to prevent or manage diabetes and other diseases.

Background

Noncommunicable diseases like diabetes and cancer create demand for therapeutic functional foods. Camel milk is rich in bioactive compounds and better tolerated than bovine milk. Ajwa dates contain phenolic compounds with antioxidant properties. The combination of fermented camel milk with Ajwa date pulp offers synergistic health benefits.

Objective

This study developed freeze-dried fermented camel milk enriched with Ajwa date pulp and evaluated its physical properties, functional properties, probiotic viability, and potential antidiabetic and anticancer activities. Six formulations were prepared using ABT-5 starter culture with or without Lacticaseibacillus rhamnosus B-1937 and Ajwa date pulp at 12% or 15% concentrations.

Results

Ajwa date pulp supplementation significantly improved dispersibility and probiotic viability while maintaining low water activity for shelf stability. The FCM15D+L formulation exhibited potent antidiabetic effects with IC50 values of 111.43 μg/mL for α-amylase and 77.21 μg/mL for α-glucosidase. Cytotoxicity against Caco-2 cells was most potent in non-ADP samples, suggesting ADP may reduce antiproliferative effects.

Conclusion

Ajwa date pulp-enriched fermented camel milk is a promising functional food with enhanced probiotic viability, improved physical properties, and significant antidiabetic potential. The study demonstrates the synergistic benefits of combining camel milk and date pulp as a functional food for combating noncommunicable diseases in vitro, with potential applications in the functional food market.
  • Published in:Foods,
  • Study Type:In Vitro Experimental Study,
  • Source: PMID: 40807635
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