Antioxidant, Antibacterial and Dyeing Potential of Crude Pigment Extract of Gonatophragmium triuniae and Its Chemical Characterization
- Author: mycolabadmin
- 1/8/2022
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Summary
Scientists discovered a rare orange-pigment-producing fungus called Gonatophragmium triuniae that has useful medicinal and practical applications. The fungus produces a natural pigment that can kill bacteria, protect against oxidative damage, and effectively dye cotton fabrics without toxic chemicals. The main active compound was identified as a phenoxazine derivative, suggesting potential uses in textiles, pharmaceuticals, and natural cosmetics as a safe alternative to synthetic pigments and antibiotics.
Background
Filamentous fungi produce natural pigments with multiple bioactivities including antioxidant and antimicrobial properties. An orange pigment-producing fungus was isolated from Maytenus rothiana leaves, identified as Gonatophragmium triuniae. Natural pigments are gaining attention as alternatives to synthetic colors due to their safety and environmental benefits.
Objective
To investigate the pigment production, bioactivity, and chemical characterization of Gonatophragmium triuniae. To evaluate the crude pigment extract for antioxidant, antibacterial, and dyeing potential, and identify the main pigment compound.
Results
G. triuniae produced satisfactory antioxidant activity with IC50 of 0.99 mg/mL and antibacterial activity against Gram-positive bacteria, with MIC values of 3.91-31.25 μg/mL. Cotton fabrics mordanted with FeSO4 showed good pigment uptake. The main pigment was identified as 1,2-dimethoxy-3H-phenoxazin-3-one (C14H11NO4, m/z 257).
Conclusion
G. triuniae represents a promising source of bioactive pigments suitable for textile and pharmaceutical applications. The identified phenoxazine derivative exhibits antioxidant and antibacterial properties alongside dyeing potential, suggesting commercial applicability in textile dyeing and pharmaceutical industries.
- Published in:Molecules,
- Study Type:Experimental Research,
- Source: PMID: 35056708