MYCOLab Ai Logo - gold and army green

Comparative Analysis of Freeze-Dried Pleurotus ostreatus Mushroom Powders on Probiotic and Harmful Bacteria and Its Bioactive Compounds

Summary

Researchers studied oyster mushrooms processed in different ways to understand their health benefits. The study found that cooked oyster mushroom powders can kill harmful bacteria and promote the growth of beneficial gut bacteria. These mushrooms also contain special particles called carbon nanodots that form during cooking and may enhance their health-promoting effects. The findings suggest oyster mushrooms could help maintain a healthy gut microbiota naturally.

Background

Pleurotus ostreatus (oyster mushroom) is widely consumed for its nutritional and medicinal properties. The mushroom contains bioactive compounds including polysaccharides, phenolics, and flavonoids that exhibit prebiotic, antimicrobial, and antioxidant properties. Heat-induced processing creates secondary compounds such as melanoidins and carbon nanodots that may enhance bioactivity.

Objective

This study explores the antimicrobial and probiotic growth stimulation benefits of freeze-dried P. ostreatus powders produced from different processing methods. The research examines polysaccharide fractions, secondary metabolites, carbon nanodots, and their effects on beneficial and harmful bacteria.

Results

OMP-CSR and OMP-TF showed highest β-glucan content (37.95% and 36.25% respectively). OMP-CL contained the highest carbon nanodots (0.00504 w/w%) with highest fluorescence intensity. OMP-CL and OMP-CSR significantly inhibited S. epidermidis growth, while OMP-CL notably promoted L. casei growth. Limited antimicrobial effects were observed against E. coli.

Conclusion

Cooked oyster mushroom powders (OMP-CL and OMP-CSR) demonstrate significant potential for gut microbiota modulation through antimicrobial activity against Gram-positive bacteria and probiotic stimulation. OMP-CL’s high carbon nanodot content may contribute to its bioactivity. Further in vitro and in vivo studies are needed to fully understand mechanisms of action.
  • Published in:Journal of Fungi,
  • Study Type:Experimental Study,
  • Source: 10.3390/jof11010001, PMID: 39852421
Scroll to Top