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Nature-themed video intervention may improve cardiovascular safety of psilocybin-assisted therapy for alcohol use disorder

Summary

Researchers tested whether watching nature videos during psilocybin therapy could improve treatment for alcohol addiction. Twenty participants received psilocybin sessions while either watching nature videos or using standard procedures with eyeshades and music. The study found that nature videos significantly reduced the blood pressure increases that normally occur with psilocybin, while maintaining the same therapeutic benefits for reducing alcohol use and promoting meaningful experiences.

Background

Psychedelic-assisted therapy with psilocybin shows promise for treating alcohol use disorder (AUD). Set and setting, particularly factors facilitating connection with nature, may positively influence the psychedelic experience and outcomes. However, randomized controlled trials of interventions to enhance set and setting for psychedelic-assisted therapy are lacking.

Objective

To assess the safety and feasibility of Visual Healing, a nature-themed video intervention designed to optimize set and setting during psilocybin-assisted therapy for alcohol use disorder in a pilot randomized controlled trial.

Results

Nineteen of 20 participants completed the 14-week study. Peak increase in post-psilocybin blood pressure was significantly less in the Visual Healing group compared to Standard procedures. Alcohol use decreased significantly in both groups with no differences between interventions. Psychedelic effects, anxiety, and stress were similar between groups.

Conclusion

Visual Healing nature-themed videos were feasible, safe, and well-tolerated during psilocybin-assisted therapy. Preliminary findings suggest potential to reduce cardiovascular risks without interfering with psychedelic experience or alcohol-related outcomes. Further studies are warranted to replicate findings.
  • Published in:Frontiers in Psychiatry,
  • Study Type:Pilot Randomized Controlled Trial,
  • Source: 37795513
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